Evidence-based articles on CBD mechanisms, clinical trial data, and practical guidance for clinicians and informed patients. We cite primary sources.
All Articles
A deep dive into randomized controlled trials, endocannabinoid system mechanisms, and the clinical evidence for CBD as a pain modulator. We examine JAMA, Lancet, and European Journal of Pain data — plus dosing considerations and the CYP3A4 drug interaction pathway physicians need to know.
Read the evidenceA review of published RCT data on CBD's effects on sleep latency, REM duration, and anxiety-related insomnia. Mechanism: GABA modulation and cortisol regulation.
Not all CBD is equal. What to look for in a Certificate of Analysis, red flags in manufacturing claims, and why cGMP certification matters for patient recommendations.
CBD inhibits CYP3A4 and CYP2D6, affecting over 60% of commonly prescribed medications. A clinical reference for checking interaction risk before patient conversations.